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Human Intestine is a hub of millions of microbes some are useful while some are pathogenic.

The relationship between children and worms is well known since ages. For all these pathological worms both clinically important and essential micro and macro nutrients are lost. Worms were also crucified for inability to gain weight, poor haemoglobin ,Gi blood loss, anaemia and even mental and behavioural changes. Hence regular de-worming was suggested in various national programs.

1.    Intermittent de-worming of school-age children can improve weight gain in some high-prevalence areas only based on analysis of recently available RCTS.AND REVIEWS.
2.    First screen followed by treatment sos if necessary can be valid approach with due practical/microbial behavior limitations in low prevalence regions.
3.    None of the previous trial is large enough to assess effects on mortality.
4.    In preschool children regular de-worming agents had little effect on weight gain or in mortality.
5.    It is premature to introduce routine de-worming mass programmes based on available evidence of consistent benefit on nutrition, hemoglobin, school attendance or school performance due to insufficient reliable information.
6.    Anthelmintic drugs need to be integrated with nutritional interventions such as micronutrient supplements to promote recovery and have a rapid effect in diagnosed infected cases or in high prevalence regions.
7.    Some earlier studies have shown positive effects on weight gain by use of deworming agents while some refuted the evidence which has created some confusion. This variability in the results may be because of unevenly distributed worms in hosts. But Cochrane meta-analysis and recent large trials in 2013 and 2012 have well studied the issue.

Dr.Yogesh Waikar,Pediatric Gastroenterologist & Liver Transplant Physician